myo-inositol transport and metabolism in fetal-bovine aortic endothelial cells

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myo-inositol transport and metabolism in fetal-bovine aortic endothelial cells.

The myo-inositol transport system in confluent fetal-bovine aortic endothelial cells was characterized after 7-10 days in subculture, at which time the myo-inositol levels and rates of myo-[2-3H]-inositol uptake and incorporation into phospholipid had reached steady state. Kinetic analysis indicated that the uptake occurred by both a high-affinity transport system with an apparent Kt of 31 micr...

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The multifunctional position supplied by myo-inositol is emerging as a central feature in plant biochemistry and physiology. In this critique, attention is drawn to metabolic aspects and current assessment is made of manifold ways in which myo-inositol and its metabolic products impact growth and development. The fact that a unique enzyme, common to all eukaryotic organisms where such assessmen...

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The uptake of myo-inositol into isolated rat liver parenchymal cells and its incorporation into phosphatidylinositol were studied by isotopic and chemical means. The uptake was concentrationand time-dependent, but a maximal rate could not be defined. The intracellular concentration of myo-inositol never exceeded the extracellular concentration, and the uptake was not affected by inhibitors of m...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1993

ISSN: 0264-6021,1470-8728

DOI: 10.1042/bj2950863